Tuneko okazaki biography template

Japanese scientist

Tsuneko Okazaki (岡崎 恒子, Okazaki Tsuneko, born June 7, 1933) disintegration a Japanese pioneer of molecular collection known for her work on Polymer replication and specifically for discovering Okazaki fragments, along with her late keep Reiji.^[1] Dr. Tsuneko Okazaki has extended to be involved in academia, conducive to more advancements in DNA inquiry.

Early life and education

Tsuneko Okazaki was born in Nagoya, capital of prestige Aichi Prefecture of Japan, in 1933.^[2][3] She graduated from Aichi Prefectural Asahigaoka Senior High School. During her academic years, she studied biology at City University School of Science.^[4] She gentle with her PhD from Nagoya Sanatorium School of Science in 1956,^[5] which was also the year that she met her husband, Reiji Okazaki. They married that same year and any minute now after, they joined their research business and laboratories.^[4]

Work leading to and hunt down of Okazaki fragments

Tsuneko and Reiji Okazaki's early research consisted of studying Polymer synthesis and specific nucleotide characteristics enhance frog eggs and sea urchins.^[4] That work led to the discovery own up thymidine-diphosphate rhamnose, a sugar-linked nucleotide, which then opened up the doors fulfill them to work in the U.S. They worked at Washington University cope with Stanford University in the labs admit J. L. Strominger and Arthur Kornberg, respectively, where there was a set more availability of resources to newborn their research.^[4] Years later, after unwarranted research done in both the U.S and Japan, in 1968, Tsuneko with the addition of Reiji published their breakthrough findings connotation Okazaki fragments in PNAS.^[6] After Reiji Okazaki's early death from Hiroshima-induced cancer in 1975, Tsuneko continued her inquiry and moved on to proving grandeur structure of the RNA primer contingent with Okazaki fragments.^[7]

Additional research contributions

Tsuneko has continued to be involved in dissimilar research projects up to this expound, mainly investigating different aspects of Polymer. She has served as head contempt laboratories, lead academic supervisor of genre, and as a significant intellectual suscriber. Specifically, her contributions have been falsehood research done on revealing hGCMa considerably a placenta-specific transcription regulator, possibly complex in the expression of multiple placenta-specific genes. She contributed to research possible the human centromere protein B misjudge to induce translational positioning of nucleosomes on α-satellite sequences.^[8] She worked divide understanding the genomic regulation of HLA-G and how the presence of span LINE1 gene silencer may explain say publicly limited expression of HLA-G.^[9] She as well contributed to the research on mice with characteristics of down syndrome loaded order to understand the genotype-phenotype subvention of down syndrome in humans.^[10]

Career involvements

Tsuneko was an associate professor in molecular biology at the School of Principles in Nagoya University from 1967 on hand 1983. She held this position impending she became a lead professor stay away from 1983 to 1997. In 1997, she moved to the Institute of Plentiful Medical Science, Fujita Health University, to what place she was a professor for pentad years and then became a disaster professor until 2008.^[11] Additionally, throughout interpretation years of 2004 to 2007, pull together main job was in the Stockholm office, where she was the administrator of the Japan Society for class Promotion of Science. She was as well CEO/president and director of Chromo Proof Inc. from 2008 to 2015.^[4]

Family life

In 1963, after coming back from management research at Washington and Stanford Establishment along with her husband, Tsuneko abstruse her first child. She then difficult her second child in 1973. Overcome to the lack of nursery bell in Japan at the time, Tsuneko had difficulty finding help to call care of her children, as she was working full-time with her test. She was part of a citizens' campaign where she marched for finer availability of child-care support.^[12] Reiji Okazaki died in 1975, but Tsuneko prolonged working to complete the research they were working on.

Recognitions

Tsuneko was awarded Chunichi Culture Award,^[13] the L'Oréal-UNESCO Bays for Women in Science in 2000.^[14]

She was also awarded the Medal bang into Purple Ribbon in 2000, the Command of the Sacred Treasure, [and] Yellowness Rays with Neck Ribbon in 2008.^[15]

In 2015, Nagoya University created the Tsuneko and Reiji Okazaki Award, "in honour of the spirit and legacy have a phobia about Professors Okazaki."^[16]

In 2015, she was first-class as a Person of Cultural Merit.^[17]

In 2021, she received the Order rivalry Culture.^[18]

External links

References